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Endocrine Abstracts

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ea0035p1149 | Thyroid Cancer | ECE2014

Prognostic significance of TERT promoter mutations in follicular cell-derived thyroid carcinomas

Melo Miguel , da Rocha Adriana Gaspar , Vinagre Joao , Batista Rui , Peixoto Joana , Celestino Ricardo , Salgado Catarina , Eloy Catarina , Lima Jorge , Amaro Teresina , Lobo Claudia , Moura Margarida , Cavaco Branca , Leite Valeriano , Cameselle-Teijeiro Jose Manuel , Carrilho Francisco , Carvalheiro Manuela , Maximo Valdemar , Sobrinho-Simoes Manuel , Soares Paula

Context: Telomerase promoter mutations (TERT) were recently described in follicular cell-derived thyroid carcinomas (FCDTC) and seem to be more prevalent in aggressive cancers.Objectives: We aimed to evaluate the frequency of TERT promoter mutations in thyroid lesions and to investigate the prognostic significance of such mutations in a large cohort of patients with differentiated thyroid carcinomas (DTC).<p class="abstext"...
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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